|
rs1203334353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs140506267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs140506267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs34075659
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants, c.671A>G (p.(Asn224Ser)) in DMRT1 and c.91C>T (p.(Arg31Cys)) in REC8, have already been described in association with azoospermia.
|
31479588 |
2020 |
|
rs150771661
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our early studies revealed a missense mutation (R242H) of GRTH in 5.8% of Japanese patient population with azoospermia.
|
31040297 |
2019 |
|
rs26279
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotype frequency distribution of rs26279 (A>G) in MSH3 was found to be significantly different between IMI and control (p < 0.05), as well as azoospermia.
|
31342644 |
2019 |
|
rs6166
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the association of the single-nucleotide polymorphisms (SNP) FSHB -211G>T (rs10835638), FSHR -29G>A (rs1394205), and FSHR c.2039A>G (rs6166) with testicular histopathology and SRR in patients with azoospermia.
|
30668782 |
2019 |
|
rs12870438
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Of these, three SNPs (rs7867029, rs7174015, and rs12870438) were found to be significantly associated with the risk of azoospermia and/or oligozoospermia in a Japanese population.
|
28975488 |
2018 |
|
rs1799983
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to assess the possible association of three genetic variants (rs2070744, rs1799983 and intron variant 4a/4b) in NOS3 gene and infertility occurrence in two groups of infertile men (idiopathic azoospermia and oligoasthenozoospermia) and fertile controls.
|
28466478 |
2018 |
|
rs7174015
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Of these, three SNPs (rs7867029, rs7174015, and rs12870438) were found to be significantly associated with the risk of azoospermia and/or oligozoospermia in a Japanese population.
|
28975488 |
2018 |
|
rs10129954
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Also, a statistically significant association between rs10129954 and azoospermia, and oligozoospermia was observed.
|
28975488 |
2018 |
|
rs11531577
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant differences in allele and genotype frequencies of SNP rs1050482 and rs11531577 in STAG3 gene as well as rs2288846 in RFX2 gene between patients with azoospermia and controls were observed.
|
29277047 |
2018 |
|
rs12348
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When we assessed the relationship between rs12348 in TUSC1 and rs2772579 in IZUMO3 and male infertility traits, we found that rs12348 in TUSC1 was significantly associated with azoospermia and oligozoospermia, but rs2772579 in IZUMO3 was not associated with male infertility.
|
28975488 |
2018 |
|
rs2070744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to assess the possible association of three genetic variants (rs2070744, rs1799983 and intron variant 4a/4b) in NOS3 gene and infertility occurrence in two groups of infertile men (idiopathic azoospermia and oligoasthenozoospermia) and fertile controls.
|
28466478 |
2018 |
|
rs2288846
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant differences in allele and genotype frequencies of SNP rs1050482 and rs11531577 in STAG3 gene as well as rs2288846 in RFX2 gene between patients with azoospermia and controls were observed.
|
29277047 |
2018 |
|
rs4045481
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The polymorphism of SNP rs4045481 in RNF212 gene might be associated with azoospermia and genotype CC of this SNP may be a risk factor of azoospermia.
|
29277047 |
2018 |
|
rs68073206
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We addressed the functional consequences of SNP rs68073206, located at the +5 position of an alternative 5' splice donor site, and observed its association with male infertility in the subjects with azoospermia, oligoasthenozoospermia and normozoospermia.
|
28367994 |
2017 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis is in favor that the MTHFR C677T polymorphism is capable of causing male infertility susceptibility, especially in Asians and the subgroup of azoospermia.
|
26584688 |
2016 |
|
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In following stratified analysis, we found that rs11614913 exhibited a significantly higher risk of asthenospermia, oligozoospermia and azoospermia.
|
26805933 |
2016 |
|
rs222859
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of G/T(rs222859) polymorphism in Exon 1 of YBX2 gene with azoospermia, among Iranian infertile males.
|
26804374 |
2016 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our meta-analysis showed that the MTHFR C677T mutation was a risk factor for male infertility in both azoospermia and oligoasthenoteratozoospermia patients, especially in Asian population.
|
26549413 |
2015 |
|
rs12870438
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The association between rs7174015 and oligozoospermia under a dominant model and between rs12870438 and azoospermia under additive and recessive models remained after correction for multiple testing.
|
25908656 |
2015 |
|
rs7174015
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The association between rs7174015 and oligozoospermia under a dominant model and between rs12870438 and azoospermia under additive and recessive models remained after correction for multiple testing.
|
25908656 |
2015 |
|
rs11204546
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Clinically, the SNPs (rs11204546 of OR2W3 and rs11677854 of GTF2A1L ) might be additional valuable molecular predictive markers for assessing the treatment of NOA patients.
|
25374392 |
2015 |
|
rs11677854
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Clinically, the SNPs (rs11204546 of OR2W3 and rs11677854 of GTF2A1L ) might be additional valuable molecular predictive markers for assessing the treatment of NOA patients.
|
25374392 |
2015 |